Generic name: flax (FLACKS) Int J Cancer 2005;116:793-8. While choosing an Omega 3 supplement, it is . Flax and flaxseed oil: An ancient medicine and modern functional food. Br J Nutr. The phase IV clinical study analyzes what interactions people who take Flax seed and Aspirin have. View abstract. View abstract. Br J Nutr 1993;69:443-53. Thompson LU, Chen JM, Li T, et al. Can J Physiol Pharmacol. National Center for Complementary and Integrative Health. 1 Severe Side Effects There are three primary types of omega-3s, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Barbiturate medicines that are prescribed for treating insomnia, controlling anxiety, or treating seizures may interfere with the effectiveness of the birth control pill. Pan A, Sun J, Chen Y, et al. Potassium helps negate the ill-effects of sodium. Thompson LU, Rickard SE, Cheung F, et al. Here are the seven side-effects of flaxseeds: 1. A total of 12 drugs are known to interact with green tea. Possible interactions include: Anticoagulant and anti-platelet drugs, herbs and supplements. Selected from data included with permission and copyrighted by First Databank, Inc. It is not certain whether flax is effective in treating any medical condition. View abstract. Learn about the medical uses, claims, and side effects of flaxseed. Cabbage - Sulconazole. Mohammadi-Sartang M, Sohrabi Z, Barati-Bodaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. Leon F, Rodriguez M, Cuevas M. Anaphylaxis to Linum. View abstract. Milder IE, Feskens EJ, Arts IC, et al. J Investig Allergol Clin Immunol. How fast does psyllium work? Drug interactions are reported among people who take Flax seed and Aspirin. Read more: What Are the Benefits of Flaxseed Oil Pills? Dietary fiber and breast cancer. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. You can get the same amount of omega-3 fatty acids in your body by consuming fewer fish oil capsules. A phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes: North Central Cancer Treatment Group N08C7. Flax can affect blood-clotting and may increase your risk of bleeding. Some medications that may interact with flaxseed oil negatively include: You should consult your doctor before using flaxseed oil if you have: Pregnant and nursing women should avoid the use of flaxseed oil. Lim TL, Pietrofesa RA, Arguiri E, et al. J Clin Endocrinol Metab 2002;87:1527-32.. View abstract. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Phytother Res 2021;35(7):3781-3791. information and will only use or disclose that information as set forth in our notice of Oral drugs. Does Flaxseed Interfere With Cholesterol Medication? Obes Rve. Sonestedt E, Borgquist S, Ericson U, et al. View abstract. Plasma phytoestrogens and subsequent breast cancer risk. Eating flaxseed in muffins or other foods seems to increase, High cholesterol. Jenkins DJ, Kendall CW, Vidgen E, et al. View abstract. Flaxseed is also taken by mouth for acne, attention deficit-hyperactivity disorder (ADHD), kidney problems in people with a disease called systemic lupus erythematosus (SLE), symptoms of menopause, breast pain, diabetes, obesity and weight loss, HIV/AIDS, depression, malaria, rheumatoid arthritis, sore throat, upper respiratory tract infections 2020;19(1):8. J Am Coll Nutr 1993;12:501-4. You may opt-out of email communications at any time by clicking on You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. View abstract. Flaxseed and prostate cancer risk. Flaxseed oil doesn't have these phytoestrogens. Do not use different formulations of flax (such as tablets, liquids, and others) at the same time, unless specifically directed to do so by a health care professional. Often youll need to take flaxseed oil a few hours before administering medications to make sure your body absorbs them properly. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. Arjmandi BH. Version: 5.01. prednisone, atorvastatin, rosuvastatin, simvastatin, ezetimibe, estradiol, Crestor, MiraLAX, Colace, docusate. Dont take flaxseed oil or flax seeds in pregnancy or while breastfeeding. 2015 Apr;145(4):749-57. View abstract. Appetite 2012;58:490-5. 2018 Feb 1;76(2):125-39. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. This article explores 9 science-backed benefits of eating flaxseed. Appl Physiol Nutr Metab 2009;34:89-98. Severe Interactions These medications are not usually taken together. What medications does flaxseed interfere with? Flaxseed and cardiovascular risk. Int J Vitam Nutr Res. Cornish SM, Chilibeck PD, Paus-Jennsen L, et al. Read more: 17 Reasons Why You Probably Need More Omega-3s in Your Diet. Blood pressure drugs, herbs and supplements. These shiny seeds are packed with other nutrients, too,. View abstract. You should also be cautious about consuming flaxseed oil if you use medications that alter your blood sugar levels. Am J Clin Nutr 1999;69:549-55. Alonso L, Marcos ML, Blanco JG, et al. Complement Ther Med. View abstract. Furthermore, some blood thinners, NSAID pain killers, hormone treatments, and certain medications for blood pressure, cholesterol, and diabetes may interact with flaxseed oil and flaxseed. You should also discuss the length of time its healthy to use it as well as a recommended dosage. Clin Rheumatol. The beneficial potential of flaxseed to reduce blood pressure (especially diastolic blood pressure) may be greater when it is consumed as a whole seed and for a duration of >12 wk. Learn about the medical uses, claims, and side effects of flaxseed. Before using flax, talk to your healthcare provider. The phase IV clinical study analyzes what interactions people who take Flaxseed and Metformin have. are using nonsteroidal anti-inflammatory drugs. Nutr Res. Mayo Clinic does not endorse companies or products. Avoid using flax together with other herbal/health supplements that can also affect blood-clotting. 2020;29(1):61-67. View abstract. Sorry, we have no data available. You need to be careful in using these supplements if you have diabetes or any other condition that affects your blood sugar levels. Simbalista RL, Sauerbronn AV, Aldrighi JM, Areas JA. Carcinogenesis 1996;17:1373-6. Natural Medicines. Am J Clin Nutr 1995;61:62-8. Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Brouwer IA, Katan MB, Zock PL. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). However, you should always talk to your primary care provider to discuss flaxseed oil dosage and safety before adding the plant oil to your daily routine. WebMD does not provide medical advice, diagnosis or treatment. National Center for Complementary and Integrative Health. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. No, it's not always safe to take flaxseed oil with other medications. Talk to your primary care provider or pharmacist to discuss flaxseed oil drug interactions. Journal of Nutrition. We avoid using tertiary references. View abstract. (2014). To provide you with the most relevant and helpful information, and understand which Hypertension. View abstract. One tablespoon of flaxseed oil has 7.26 grams. The effectiveness of your oral contraceptives or hormonal therapy may also be affected by flaxseed meal consumption. Summary: Drug interactions are reported among people who take Flaxseed and Anastrozole. Effects of flaxseed supplements on blood pressure: a systematic review and meta-analysis of controlled clinical trial. However, it may cause undesirable side effects if you have a preexisting medical condition, use certain medications, or take the wrong dosage. These medications are not usually taken together. Here are 5 potential benefits of 5-HTP, Ritual is a subscription-based vitamin company that offers protein powders and multivitamins for people of all ages. Adlercreutz H, Fotsis T, Bannwart C, et al. Human metabolism of mammalian lignan precursors in raw and processed flaxseed. Cunnane SC, Ganguli S, Menard C, et al. Examples of barbiturates and medications that have barbiturate actions include: Felbatol (felbamate) Anaphylaxis caused by linseed (flaxseed) intake. Is flaxseed good for everyone? Circulating enterolactone and risk of endometrial cancer. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. However, research has shown that flax may not be effective in treating this condition. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Obstet Gynecol 2002;100:495-504.. View abstract. Drink plenty of water each day while you are taking this product. Limited animal studies have found that flaxseed and flaxseed oil do not interfere with actions of tamoxifen or trastuzumab (medications used for breast cancer treatment) and may even enhance their effectiveness. J Nutr 2010;140:293-7. 2013;23(6):446-7. What should I know regarding pregnancy, nursing and administering Flaxseed to children or the elderly. Morshedzadeh N, Rahimlou M, Shahrokh S, Karimi S, Mirmiran P, Zali MR. Menopause 2006;13:631-42. Kuijsten A, Hollman PC, Boshuizen HC, et al. View abstract. Int J Cancer 2004;111:444-50.. View abstract. The effects of flaxseed supplementation on metabolic syndrome parameters, insulin resistance and inflammation in ulcerative colitis patients: An open-labeled randomized controlled trial. There are many studies currently under way to link the use of flaxseed oil with positive health benefits, but there is no standard use of the supplement. Cats require certain vitamins, minerals, and . Thompson LU, Rickard SE, Orcheson LJ, Seidl MM. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Consult with a licensed healthcare professional before using any herbal/health supplement. Taylor, C. G., Noto, A. D., Stringer, D. M., Froese, S., and Malcolmson, L. Dietary milled flaxseed and flaxseed oil improve N-3 fatty acid status and do not affect glycemic control in individuals with well-controlled type 2 diabetes. The information provided in this blog post is intended for informational purposes only and should not be used to diagnose, treat, cure, or prevent any health condition in animals. Nutr Rev 2004;62:18-27. J Res Med Sci. Wong H, Chahal N, Manlhiot C, Niedra E, McCrindle BW. Nutr Cancer 2007;58:162-70. Goyal A, et al. Use caution when adding flaxseed oil to your diet or using it as a supplement. Learn how we can help 3.9k views Reviewed >2 years ago Thank Dr. John Munshower and 4 doctors agree 1 thank Ann N Y Acad Sci 1990;595:281-90. You may be eager to find a supplement to boost the omega-3 fatty acids in your body. Lancet 1982;2:1295-9. Am J Clin Nutr 1997;66:591-8. https://naturalmedicines.therapeuticresearch.com. Store at room temperature away from moisture and heat. View abstract. Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. View abstract. Khalesi S, et al. Even though the nutritional profile of flaxseeds may be useful for improving the function of the Thyroid, it is important to consider that there is also one particular concerning the fact that need to be taken into account. J Allergy Clin Immunol 1996;98:469-70. information submitted for this request. Flax should not be used in place of medication prescribed for you by your doctor. Vomiting and nausea may also be signs of an allergy. February 24, 2023. Flax seeds are very beneficial for health because they contain a good amount of omega-3 fatty acids that cuts down the risk of heart diseases by controlling cholesterol. Am J Clin Nutr 2001;73:1094-100. The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women. Flaxseed reduces some risk factors of cardiovascular disease. J Nutr 2004;134:919-22. Low adherence may be a contributing factor leading to uncontrolled blood pressure in patients. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. Flaxseed is considered to be a goitrogen. Flax seeds are considered to help with constipation. J Natl Cancer Inst 2007;99:475-86. 2019:1-8. Mohammadi-Sartang M, Mazloom Z, Raeisi-Dehkordi H, Barati-Bodaji R, Bellisimo N, Totosy de Zepetnek JO. The effects of dietary flaxseed on cardiac arrhythmias and claudication in patients with peripheral arterial disease (1). You should discontinue and avoid the use of flaxseed oil if you notice itching, swelling, redness, or hives when you ingest it. 2013 Dec;62(6):1081-9. Effects of dietary flaxseed in women with cyclical mastalgia. View abstract. Mani UV, Mani I, Biswas M, Kumar SN. Kidney Int 1995;48:475-80. J Steroid Biochem Mol Biol 1994;50:205-12.. View abstract. The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial. Pruthi S, Qin R, Terstreip SA, et al. Research is strongly showing that long-term use of metformin and at high doses (1.5mg or higher daily) can deplete levels of vitamin B12. Flaxseed oil contains ALA, which your body primarily uses as a source of energy, according to Harvard T.H. Cancer Causes Control 2000;11:679-85. Check your medications for potential interactions with herbal supplements Popular Interaction Pages. Giovannucci E, Rimm EB, Colditz GA, et al. View abstract. Teas have been used as a natural remedy to soothe stomach upset for thousands of years. Asia Pac J Clin Nutr. Therefore, the quality and contents of flaxseed oil arent regulated and standardized. All rights reserved. Flaxseed is used for constipation, diabetes, high cholesterol, obesity, and swelling of the kidneys in people with lupus. Atherosclerosis 1998;136:367-75. Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W. Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. J Diet Suppl 2011;8:257-65. Clark WF, Parbtani A, Huff MW, et al. We comply with the HONcode standard for trustworthy health information. A single copy of these materials may be reprinted for noncommercial personal use only. 2015 Apr;145(4):758-65. Flaxseed can be added to hot cereal, muffins, pancakes, salads, salad dressings, yeast breads and more. 2019;38(7):1961-1969. Koizumi Y, Arai H, Nagase H, Kano S, Tachizawa N, Sagawa T, Yamaguchi M, Ohta K. [Case report: anaphylaxis caused by linseed included in baked bread]. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition. Flaxseed and flaxseed oil. This may be problematic if you have a health condition that causes bleeding or if youre on certain medications that may lead to bleeding, such as blood thinners. Crawford M, Galli C, Visioli F, et al. The phase IV clinical study analyzes what interactions people who take Flaxseed and Anastrozole have. Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: a controlled, crossover trial. Flaxseed interacts with 583 drugs . Cockerell KM, Watkins AS, Reeves LB, et al. Some medications that may interact with flaxseed oil negatively include: those that alter your blood flow and bleeding, including: aspirin blood thinners, like warfarin (Coumadin) and. J Altern Complement Med 2020;26(9):799-806. Zeleniuch-Jacquotte A, Lundin E, Micheli A, et al. Flaxseed might lower blood pressure. Hadi A, Askarpour M, Salamat S, Ghaedi E, Symonds ME, Miraghajani M. Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response meta-analysis of sixty-two randomized controlled trials. Flaxseed in pediatric hyperlipidemia: a placebo-controlled, blinded, randomized clinical trial of dietary flaxseed supplementation for children and adolescents with hypercholesterolemia. If you have a condition or take a medication that lowers your blood pressure, adding this supplement to your diet could cause complications. View abstract. View abstract. It may take 1 to 3 days before this medication starts working. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Monitor your blood sugar closely. View abstract. Lemay A, Dodin S, Kadri N, et al. Finnegan YE, Minihane AM, Leigh-Firbank EC, et al. View abstract. Explore (NY) 2021. Flaxseed oil is available in liquid and capsule form. Reducing atherogenic risk in hyperlipemic humans with flaxseed supplementation: a preliminary report. Rich in omega-3 fatty acids, flaxseed oil is gaining ground as a functional food with many potential health benefits. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. View abstract. Colli MC, Bracht A, Soares AA, et al. Haggans CJ, Travelli EJ, Thomas W, et al. Taking flaxseed along with medications that lower blood pressure might cause blood pressure to go too low. J Womens Health (Larchmt) 2008;17:355-66. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. 2013 Apr;17(2):275-81. Rickard SE, Yuan YV, Thompson LU. This will help prevent any negative reactions that might arise. 2015;145:758. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects.